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Acknowledgements

Introduction

Background
Objectives of this Document
Sediment Assessment Approach
Roadmap to this Guidance

Overview of Processes Affecting Bioavailability
That Could Be Considered in Developing a Conceptual Site Model

Processes Affecting Bioavailability
Scoping the Problem
Date Quality Objectives
Community Stakeholder Identification, Engagement, and Contributions

Sediment Screening

Screening Approaches
Screening Summary

Bioavailability to Benthic Invertebrates

Tools for Assessing Benthic Invertebrate Bioavailability
Application of Bioavailability Tools in Risk Assessment and Risk Management

Bioavailability to Fish and Water-Column Invertebrates

Conceptual Site Model for Water-Column Organisms
Tools and Measures
Application of Bioavailability Tools in Risk Assessment and Risk Management

Bioavailability to Wildlife

Conceptual Site Model for Wildlife Receptors
Chemical Approaches
Biological Approaches
Basic Empirical Wildlife Exposure Models
Process-Based Predictive Exposure Models
Application of Bioavailability Measures in Risk Assessment and Risk Management

Bioavailability in Plants

Chemical Approaches for Plant Exposure Assessment
Biological Approaches
Modeling Plant Bioavailability and Bioaccumulation
Application of Bioavailability Tools in Risk Assessment and Risk Management

Bioavailability in Human Populations

Direct Contact
Fish and Shellfish (Aquatic Invertebrate) Ingestion
Wildlife Ingestion
Plant Ingestion
Application of Bioavailability Tools in the Human Health Pathway

Incorporation of Bioavailability into Risk Assessment and Risk Management

Risk Assessment
Risk Management
Summary

References

Appendices

Appendix A. Selected References on Bioavailability in Aquatic Systems
Appendix B. Categories of Contaminants
Appendix C. Bioavailability Tools and Methods
Appendix D. Case Study Questionnaire and Summaries
Appendix E. ITRC Contaminated Sediments Team Contacts
Appendix F. Glossary
Appendix G. Acronyms

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